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Akathisia can be misinterpreted as psychotic agitation; if the patient is not responding to acute treatment with an antipsychotic, rule out akathisia before administering more antipsychotic medication.

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In contrast, 2 studies reporting poorer mood outcome in obese patients with BD noted more evidence of greater baseline bipolar illness severity in obese compared to nonobese patients, including longer illness duration and chronic illness course as well as greater number of past mood episodes, longer duration of acute episode, and higher mean baseline Hamilton Depression Rating Scale score.

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Using information from the Danish national twin registry we aim to include all MZ twins in Denmark suitable for the study and diagnosed within the schizophrenia spectrum.

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Depression is the big problem in non-manic versions of bipolar disorder (these versions include Bipolar II, and “softer” versions, as described in the Diagnosis section of this website).

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Background: Galantamine is an acetylcholinesterase inhibitor with allosteric potentiating effects on nicotinic receptors (nAChR) and memantine is a weak NMDA-antagonist with preferential affinity against the excitatory-inhibitory synapses in cortical networks.

At discharge, the SCZ group performed more poorly in the LSF condition than the other groups, and showed the greatest degree of performance decline collapsed over HSF and LSF conditions, although the latter finding was not significant when controlling for visual acuity.

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Side-effect profiles of new antipsychotic agents.

These medications are usually most effective when they are combined with psychosocial treatment.

Ziprasidone is a medicine licensed for the treatment of schizophrenia and bipolar disorder in adults.

Murray MJ, Peruzzi WT, Lumb PD, Task Force of the American College of Critical Care Medicine (ACCM) of the Society of Critical Care Medicine (SCCM), American Society of Health-System Pharmacists (ASHP), American College of Chest Physicians: Clinical practice guidelines for the sustained use of sedatives and analgesics in the critically ill adult.

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Almost three quarters of patients switched from their first medication to a different medication.

Analysis of daily-diary data revealed that the interaction of LPFC activity and interpersonal conflict predicts daily mood and behavior.

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In a 2014 study, researchers found a variant in the GRM3 gene that was associated with a two- to three-fold increase in the risk of developing schizophrenia or alcohol dependence and an approximately three-fold greater risk of developing bipolar disorder.

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The functional GRM3 Kozak sequence variant rs148754219 affects the risk of schizophrenia and alcohol dependence as well as bipolar disorder.

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Medical and biological laboratory tests should exclude diseases and injuries, diseases and injuries of other organs, psychoactive substances, and toxins as causes of symptoms of psychosis before any psychiatric illness can be diagnosed.

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In this study, we explore for the first time the relationship between HPA axis activity, WM microstructure and clinical outcome in FEP patients.

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Men with bipolar disorder also tend to have higher rates of substance abuse (drugs, alcohol) than women.

Note: The symptoms are not solely a manifestation of oppositional behavior, defiance, hostility, or a failure to understand tasks or instructions.

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Background: Cognitive remediation (CRT) has shown promising results for ameliorating cognitive impairment in schizophrenia.

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Background: In the controlled trials of second generation antipsychotics (SGA) compared with first generation antipsychotics (FGA) the rates of movement disorders were much lower in SGA.

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Kooy published data on one of the most consistent findings in schizophrenia research, which is the dysfunction of the energy metabolism.

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Methods: To decompose neural elements of performance, we used variations of pro- and anti-tasks while measuring the visual steady-state response (vSSR) with dense array EEG during response preparation.

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