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Comment. These "glass half-full, half-empty" results suggest that women at low risk for fracture may feel comfortable taking a break after 5 years of alendronate treatment. Other women, particularly those with prior fractures or very low bone density, may choose to continue.
Is zoledronic acid used for osteoporosis?
Zoledronic acid is a potent intravenous bisphosphonate. Once-yearly infusion of zoledronic acid 5 mg is a new treatment option for osteoporosis. Zoledronic acid 4 mg (usually infused every 3–4 weeks) is used to treat hypercalcaemia and to prevent skeletal-related events in people with malignancies.
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